Mamta Malik
PDM Dental College and Research Institute, India
Title: Circulating Omentin-1-A new adipokine with diagnostic and therapeutic role in TMJ Disorders: Advanced endeavor to dental field
Biography
Biography: Mamta Malik
Abstract
Introduction: Temporomandibular Disorders (TMDs) are prominent among orofacial pain with the evidence that pathogenesis of painful TMDs is contributed by abnormal levels of cytokines resulting in alteration in ant-inflammatory cytokines level. One such anti-inflammatory cytokine is omentin-1. The aim of this study was to investigate the diagnostic and therapeutic role of omentin-1 in chronic painful TMDs.
Materials & Methodology: 120 subjects were included in the study with Group-A (n=60) having/with history of chronic painful TMDs as study group and Group-B (n=60) normal TMJ as control group. Circulating omentin-1 protein levels weremeasured using colorimetric ELISA kit. SPSS package was used to find association between omentin-1 levels and painful
TMDs with respect to age and sex. Results: Circulating omentin-1 protein levels were significantly less in the study group as compared to controls.
Conclusion: Omentin-1 plays an important role in the pathogenesis of chronic TMDs and effective interventions which can alter the level o omentin-1 have a potential use in the management of chronic pain in TMDs.